An increasing number of crystal structures available on one side, and the boost of computational power available for computer-aided drug design tasks on the other, have caused that the structure-based drug design tools are intensively used in the drug development pipelines.Docking and molecular dynamics simulations, key representatives of the struc
Introduction:Mucormycosis is an aggressive-progressive invasive fungal infection caused by mold fungi in the division of mucorales of the zygomycetes class with high mortality, and is the most common fungal infection in patients with hematologic malignancies.Methods:This study retrospectively evaluated patients with mucormycosis sww x diagnosis bet
In the context that demonhorns edge the European Commission has the right of initiative to propose new legislation, we identified a series of questions addressed to the Commission by MEPs between 1995 and 2015 on the repatriation of corpses within the EU.This inventory aims to provide an overview of the questions and their correlative answers in or
Abstract Induction tech lighting tellium of hypothermia during hibernation/torpor enables certain mammals to survive under extreme environmental conditions.However, pharmacological induction of hypothermia in most mammals remains a huge challenge.Here we show that a natural product P57 promptly induces hypothermia and decreases energy expenditure i